betahistine | Betagistin Canon tablets 24 mg 20 pcs.

release form

tablets



packaging 20 pcs

Pharmacological action of

Betagistin is a histaminergic that improves microcirculation.

Pharmacodynamics

Agonist of the H1 receptors of the vessels of the inner ear and an antagonist of the H3 receptors of the vestibular nuclei of the central nervous system. By direct agonistic action on the H1 receptors of the vessels of the inner ear, and indirectly through exposure to H3 receptors it improves microcirculation and capillary permeability, normalizes endolymph pressure in the labyrinth and cochlea, and increases blood flow in the basilar artery.

It has a pronounced central effect, being an inhibitor of the H3 receptors of the vestibular nerve nuclei. It improves the conductivity in the neurons of the vestibular nuclei at the level of the brain stem.

The clinical manifestation of these properties is a decrease in the frequency and intensity of dizziness, a decrease in tinnitus, and an improvement in hearing if it is reduced.

Pharmacokinetics

Absorbed rapidly, binding to plasma proteins is low. The time required to reach Cmax is 3 hours.

It is almost completely excreted by the kidneys as a metabolite (2-pyridylacetic acid) within 24 hours. T1 / 2 - 3-4 hours.

Indications

treatment and prevention of vestibular dizziness of various origins

syndromes including dizziness and headache, tinnitus, progressive hearing loss, nausea and vomiting

disease or Meniere's syndrome.

Use during pregnancy and lactation

Insufficient data to evaluate the effects of betahistine during pregnancy and lactation. In this regard, it is not recommended to take during pregnancy. At the time of treatment, it is necessary to stop breastfeeding.

Composition

1 tablet contains:

Active ingredient: betahistine dihydrochloride 24 mg

Excipients: MCC lactose (milk sugar) citric acid silicon monohydrate colloidal dioxide (aerosil) crospovidone talc magnesium talc.

Dosage and Administration

Inside, with meals. 1 / 2-1 tablets 3 times a day.

Improvement is usually noted already at the beginning of therapy. A stable therapeutic effect occurs after two weeks of treatment and can increase over several months of treatment. The treatment is long. The duration of the drug is selected individually.

Side effects

Gastrointestinal disorders, allergic reactions from the skin (skin rash, itching, urticaria), Quincke edema.

Drug Interactions

Betahistine's efficacy is reduced by antihistamines.

Overdose

Symptoms: nausea, vomiting, convulsions.

Treatment: gastric lavage, activated carbon intake, symptomatic therapy.

Storage Conditions

In a dry, dark place at a temperature not exceeding 25 РC. Keep out of reach of children.

Shelf life

2 years.

Deystvuyushtee substance

Betahistine

Terms of release from

pharmacies by prescription

Dosage PMA



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For adults as prescribed by a doctor