ammonium Hlytsyrryzynat |
Special Price
$29.44
Regular Price
$41.00
In stock
SKU
BID464514
Latin name
Epigen intim
Epigen intim
Latin name
Epigen intim
Packaging
In a plastic bottle with a dispenser of 15 ml of the product.
Pharmacological action
Pharmacotherapeutic group
Antiviral immunostimulating drug.
ATX code
D06BB
Pharmacological properties of
Pharmacodynamics
Active ingredient of the drug Epigen Intimate is activated glycyrrhizic acid, obtained by extraction from plant materials (licorice root).
Activated glycyrrhizic acid has a complex effect, which includes immunostimulating, antiviral, anti-inflammatory, antipruritic and regenerative.
Activated glycyrrhizic acid induces the production of its own interferons. The immunostimulating effect is manifested by an increase in the number and activity of T - lymphocytes, a decrease in the concentration of immunoglobulin G and an increase in the concentration of immunoglobulin A and M.
Activated glycyrrhizic acid has an antiviral effect on various types of DNA and RNA viruses in vitro and in vivo (Varicella Zoster herpes simplex virus type 1 and 2 cytomegalovirus, various types of human papillomavirus, including oncogenic). Activated glycyrrhizic acid interrupts the replication of viruses in the early stages, causes the virion to exit the capsid, thereby preventing its penetration into the cells. Activated glycyrrhizic acid inactivates these viruses in concentrations that are not toxic to normally functioning cells. Mutant strains of viruses that are resistant to acyclovir and iodouridine are also highly sensitive to glycyrrhizic acid, as are non-mutant strains.
The anti-inflammatory activity of activated glycyrrhizic acid is combined with a stimulating effect on humoral and cellular factors of immunity. Activated glycyrrhizic acid significantly inhibits the release of kinins and prostaglandin synthesis by connective tissue cells in the inflammation zone. The regenerating effect is due to improved repair of the skin and mucous membranes.
Pharmacokinetics
When applied topically and topically, activated glycyrrhizic acid is deposited in the lesion. Systemic absorption occurs slowly. The drug is found in the blood in trace amounts.
Use during pregnancy and lactation
The drug is approved for use during the entire period of pregnancy and lactation.
Dosage and Administration
Topically, intravaginally and intraurethrally.
Shake the bottle before use. When using the cylinder, keep it upright.
For external use, the drug is applied to the entire affected surface of the skin from a distance of 4-5 cm by 1-2 valve presses, which is the optimal therapeutic dose.
For intravaginal use of the drug, a special nozzle with a spray is attached. Remove the valve from the spray bottle and put on the nozzle valve. Then, insert the nozzle into the vagina and inject it by 1-2 pressing the nozzle, which is the optimal therapeutic dose.
When used by men, in addition to external application, the drug is injected into the external opening of the urethra by 1-2 pressing the atomizer valve.
In case of herpesvirus infection type I, shingles, the drug is recommended to be used 6 times a day for the lesion for 5 days. With a stubborn course of the infectious process, the treatment period is extended until the symptoms of the disease completely disappear.
In case of herpesvirus infection type II (genital herpes), cytomegalovirus infection is recommended to be applied 5 times a day for 14 days externally and intravaginally, after relief of relapse - externally and intravaginally 3 times a day for 10 days.
In order to prevent recurrence of genital herpes and cytomegalovirus infection, the drug is recommended to be applied topically and intravaginally from 18-20 days of the menstrual cycle until the end of menstruation 2 times a day in the morning and evening.
In case of human papillomavirus infection, the drug is recommended to be used:
until removal of genital warts - 3 times a day during the entire period of etiotropic therapy.
against the background of destruction - 5 times a day for 10 days or more until complete healing.
for prophylaxis of the next relapse 3 times a day for 1 month.
To prevent the progression of human papillomavirus infection, it is recommended to use it before and after sexual intercourse, as well as when provoking factors (stress, overwork, respiratory viral infections, microflora disturbance, antibiotic intake, cytostatics) - 3 times a day intravaginally and externally during the entire period of exposure to provoking factors.
For bacterial vaginosis, nonspecific vulvovaginitis, and candidal vulvovaginitis: the drug is recommended to be administered intravaginally 3-4 times a day for 7-10 days. If necessary, repeat the treatment after 10 days. In case of provoking factors (respiratory viral infections, taking antibiotics, cytostatics) - 3 times a day intravaginally and externally during the entire period of exposure to provoking factors.
In cases of discomfort in the genital area, accompanied by itching, burning and dry mucous membranes: 2 times a day (morning and evening) for 2-3 weeks. In order to prevent discomfort, apply regularly after intercourse.
As a prophylactic antiviral agent, the drug is recommended to be used before and after sexual intercourse.
Side effects
Individual intolerance to the components of the drug is possible.
In rare cases, local allergic reactions are possible, including in the form of contact dermatitis.
Drug Interaction
No interaction with major groups of drugs used for complex treatment in these diseases (antibiotics and antiseptics, anti-inflammatory and analgesic agents) has been detected.
Synergies have been found with the simultaneous use of activated glycyrrhizic acid and other antiviral drugs, in particular acyclovir derivatives, iodouridine, interferon and other immunomodulators.
Storage conditions
At temperatures from 15 ° to 30 РC, out of the reach of children.
Shelf life
3 years. Do not use after expiration date.
Deystvuyushtee substance
AMMO glycyrrhizinate
Terms and conditions
without prescription
Skin type
For all types
B.Braun Medical SA, Spain
Epigen intim
Packaging
In a plastic bottle with a dispenser of 15 ml of the product.
Pharmacological action
Pharmacotherapeutic group
Antiviral immunostimulating drug.
ATX code
D06BB
Pharmacological properties of
Pharmacodynamics
Active ingredient of the drug Epigen Intimate is activated glycyrrhizic acid, obtained by extraction from plant materials (licorice root).
Activated glycyrrhizic acid has a complex effect, which includes immunostimulating, antiviral, anti-inflammatory, antipruritic and regenerative.
Activated glycyrrhizic acid induces the production of its own interferons. The immunostimulating effect is manifested by an increase in the number and activity of T - lymphocytes, a decrease in the concentration of immunoglobulin G and an increase in the concentration of immunoglobulin A and M.
Activated glycyrrhizic acid has an antiviral effect on various types of DNA and RNA viruses in vitro and in vivo (Varicella Zoster herpes simplex virus type 1 and 2 cytomegalovirus, various types of human papillomavirus, including oncogenic). Activated glycyrrhizic acid interrupts the replication of viruses in the early stages, causes the virion to exit the capsid, thereby preventing its penetration into the cells. Activated glycyrrhizic acid inactivates these viruses in concentrations that are not toxic to normally functioning cells. Mutant strains of viruses that are resistant to acyclovir and iodouridine are also highly sensitive to glycyrrhizic acid, as are non-mutant strains.
The anti-inflammatory activity of activated glycyrrhizic acid is combined with a stimulating effect on humoral and cellular factors of immunity. Activated glycyrrhizic acid significantly inhibits the release of kinins and prostaglandin synthesis by connective tissue cells in the inflammation zone. The regenerating effect is due to improved repair of the skin and mucous membranes.
Pharmacokinetics
When applied topically and topically, activated glycyrrhizic acid is deposited in the lesion. Systemic absorption occurs slowly. The drug is found in the blood in trace amounts.
Use during pregnancy and lactation
The drug is approved for use during the entire period of pregnancy and lactation.
Dosage and Administration
Topically, intravaginally and intraurethrally.
Shake the bottle before use. When using the cylinder, keep it upright.
For external use, the drug is applied to the entire affected surface of the skin from a distance of 4-5 cm by 1-2 valve presses, which is the optimal therapeutic dose.
For intravaginal use of the drug, a special nozzle with a spray is attached. Remove the valve from the spray bottle and put on the nozzle valve. Then, insert the nozzle into the vagina and inject it by 1-2 pressing the nozzle, which is the optimal therapeutic dose.
When used by men, in addition to external application, the drug is injected into the external opening of the urethra by 1-2 pressing the atomizer valve.
In case of herpesvirus infection type I, shingles, the drug is recommended to be used 6 times a day for the lesion for 5 days. With a stubborn course of the infectious process, the treatment period is extended until the symptoms of the disease completely disappear.
In case of herpesvirus infection type II (genital herpes), cytomegalovirus infection is recommended to be applied 5 times a day for 14 days externally and intravaginally, after relief of relapse - externally and intravaginally 3 times a day for 10 days.
In order to prevent recurrence of genital herpes and cytomegalovirus infection, the drug is recommended to be applied topically and intravaginally from 18-20 days of the menstrual cycle until the end of menstruation 2 times a day in the morning and evening.
In case of human papillomavirus infection, the drug is recommended to be used:
until removal of genital warts - 3 times a day during the entire period of etiotropic therapy.
against the background of destruction - 5 times a day for 10 days or more until complete healing.
for prophylaxis of the next relapse 3 times a day for 1 month.
To prevent the progression of human papillomavirus infection, it is recommended to use it before and after sexual intercourse, as well as when provoking factors (stress, overwork, respiratory viral infections, microflora disturbance, antibiotic intake, cytostatics) - 3 times a day intravaginally and externally during the entire period of exposure to provoking factors.
For bacterial vaginosis, nonspecific vulvovaginitis, and candidal vulvovaginitis: the drug is recommended to be administered intravaginally 3-4 times a day for 7-10 days. If necessary, repeat the treatment after 10 days. In case of provoking factors (respiratory viral infections, taking antibiotics, cytostatics) - 3 times a day intravaginally and externally during the entire period of exposure to provoking factors.
In cases of discomfort in the genital area, accompanied by itching, burning and dry mucous membranes: 2 times a day (morning and evening) for 2-3 weeks. In order to prevent discomfort, apply regularly after intercourse.
As a prophylactic antiviral agent, the drug is recommended to be used before and after sexual intercourse.
Side effects
Individual intolerance to the components of the drug is possible.
In rare cases, local allergic reactions are possible, including in the form of contact dermatitis.
Drug Interaction
No interaction with major groups of drugs used for complex treatment in these diseases (antibiotics and antiseptics, anti-inflammatory and analgesic agents) has been detected.
Synergies have been found with the simultaneous use of activated glycyrrhizic acid and other antiviral drugs, in particular acyclovir derivatives, iodouridine, interferon and other immunomodulators.
Storage conditions
At temperatures from 15 ° to 30 РC, out of the reach of children.
Shelf life
3 years. Do not use after expiration date.
Deystvuyushtee substance
AMMO glycyrrhizinate
Terms and conditions
without prescription
Skin type
For all types
B.Braun Medical SA, Spain
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