amino acids for parenteral POWER | Cabiven central container 1540 ml, 4 pcs.

Special Price $113.16 Regular Price $132.00
In stock
SKU
BID463701
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Latin name

Kabiven
Latin name

Kabiven

Release form

Emulsion for infusion



packaging 4 pcs

Pharmacological action

Itraconazole is a derivative of triazole.

Irunin inhibits (disrupts) the synthesis of ergosterol, which is an important component of the cell membrane of fungi, Unlike chylomicrons, Intralipid does not contain cholesterol and apolipoprotein esters, and its phospholipids are higher.

Three-chamber bag with a unique shape, ports that do not contain aluminum.

Indications

Parenteral nutrition for adults and children 2 years of age and older, when oral or enteral nutrition is impossible, insufficient or contraindicated.

Contraindications

known hypersensitivity to egg or soy proteins or any auxiliary component of the drug

severe hyperlipidemia

severe hepatic insufficiency

severe coagulation disorders

requiring insulin administration in an amount of more than 6 PIECES / h

pathologically increased plasma concentration of any of the

electrolytes included in the preparation general contraindications for infusion therapy: acute pulmonary edema, hyperhydration, decompensated heart failure, hypotonic dehydration

unstable conditions (for example, post-traumatic , uncompensated diabetes mellitus, acute myocardial infarction, decompensated metabolic acidosis, severe sepsis and hyperosmolar coma).

Caution: impaired lipid metabolism due to kidney failure, diabetes mellitus, pancreatitis, impaired liver function, hypothyroidism (with hypertriglyceridemia), or sepsis. With the introduction of the drug Kabiven® to the central patient with such disorders, careful monitoring of the concentration of triglycerides in the blood plasma is necessary. Kabiven® Central is intended primarily for patients older than 2 years. In children under 2 years of age, Kabiven® Central can be used only for health reasons in the absence of special adapted amino acid solutions containing taurine (Aminoven infant). Premature infants and low birth weight babies may have impaired fat metabolism. Carefully monitor triglyceride levels.

Pregnancy and lactation

No specific safety studies have been carried out on the use of Kabiven Central during pregnancy and lactation. Before prescribing Kabiven Central during pregnancy and lactation, the potential benefits of therapy for the mother and the possible risk to the fetus or infant should be carefully evaluated.

Composition

Active substances: dextrose solution 19% 790 ml Vamin 18 Novum solution 450 ml intralipid 20% 300 ml.

Dosage and administration

Single-use infusion solution only. The drug is administered intravenously, only in the central veins. The infusion can be continued for as long as the clinical condition of the patient requires, based on the daily requirement for glucose, lipids and amino acids. The dose of the drug and the rate of infusion are determined by the patient’s ability to excrete lipids and metabolize glucose. Kabiven Central is available in four sizes of bags, designed for patients with normal, moderately increased or reduced need for nutrients. Complete parenteral nutrition may require the addition of vitamins, electrolytes, and trace elements.

The dose should be selected individually, and when choosing the volume of the bag should take into account the patient's condition, body weight and need for nutrients.

In obese patients, the dose should be set based on ideal body weight.

In patients with moderate or severe catabolic stress with or without malnutrition, the need for amino acids is 1-2 g / kg / day, which approximately corresponds to the need for nitrogen of 0.15-0.3 g / kg / day. This corresponds to 27-40 ml of central Kabiven per 1 kg of body weight per day.

In patients without catabolic stress, the need for amino acids is 0.7-1.3 g / kg / day, which is equal to the need for nitrogen 0.1-0.2 g / kg / day. This corresponds to 19-38 ml of central Cabiven per 1 kg of body weight per day.

Maximum daily dose of

Adults: 40 ml / kg / day. This is 1 bag (the largest - 2566 ml) for a patient weighing 64 kg and provides 1.3 g of amino acids / kg / day (0.21 g of nitrogen / kg / day), 31 kcal / kg / day of non-protein energy, 3.9 g of glucose / kg / day and 1.6 g fat / kg / day. The maximum daily dose depends on the clinical condition of the patient and may vary.

For children aged 2-10 years: infusion of the drug should begin with a low dose of 14-28 ml / kg. The dose should be increased by 10-15 ml / kg / day, up to a maximum of 40 ml / kg / day.

Children over 10 years of age: Use the same doses as adults.

Infusion rate

The infusion rate should not exceed 2.6 ml / kg / h, which corresponds to a dextrose (glucose) infusion rate of 0.25 g / kg / h, amino acids 0.09 g / kg / h and lipids 0.13 g / kg / h. The recommended duration of infusion of central Kabiven is 12-24 hours.

Drug interaction

Heparin in therapeutic doses causes a transient release of lipoprotein lipase into the bloodstream, which may lead initially to an increase in plasma lipolysis, and then to a transient decrease in TG clearance. Insulin can also affect lipase activity, but there is no evidence of an adverse effect of this factor on the therapeutic value of the drug. Vitamin K1, contained in soybean oil, is an antagonist of coumarin derivatives, therefore it is recommended to carefully monitor blood coagulation in patients receiving these drugs. Kabiven Central can only be mixed with those medicines and nutrient solutions, for which compatibility with it is confirmed, for example: Vitalipid N adult and Vitalipid N children Soluvit N Addamel N Dipeptiven. Mixing solutions should be carried out under aseptic conditions.

Overdose

Symptoms: as a result of impaired ability to remove fat, the development of fat overload syndrome - hyperlipidemia, fever, hepatosplenomegaly, anemia, leukopenia, thrombocytopenia, coagulopathy and coma.

Treatment: discontinuation of lipid infusion, symptomatic therapy.

Storage conditions

Do not store above 25 РC. Do not freeze.

Shelf life

2 years.

Deystvuyushtee substance

Aminokislot for parenteral nutrition

dosage form

emulsion for infusion

Possible product names

Cabiven 1400 center. emulsion. d / inf. 1540ml X4 (R)

Kabiven 1400 center. emulsion. d / inf. 1540ml X4 (R) /! Until 01.10./

Kabiven 1400 center. emulsion. d / inf. 1540ml X4 (R)! Until 04.10g /

Kabiven 1400 center. emulsion. d / inf. 1540ml X4 (R) /! Until 08.09g. /

Kabiven 1400 center. emulsion. d / inf. 1540ml X4 /! Until 09.10g / (R)

Fresenius Kaby, Germany

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