Acetylcysteine | Fluimucil granules for solution for oral administration 200 mg sachet 20 pcs.

Special Price $13.58 Regular Price $22.00
In stock
SKU
BID462897
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Release form

Granules for solution for oral administration.
Release form

Granules for solution for oral administration.

Packing

20 pcs.

Pharmacological action

Fluimucil is a mucolytic drug with antioxidant properties.

Thins sputum, increases its volume and facilitates its separation.

The action of acetylcysteine ​​is associated with the ability of its sulfhydryl groups to break the intramolecular and intermolecular disulfide bonds of acid mucopolysaccharides of sputum, which leads to the depolarization of mucoproteins and a decrease in the viscosity of sputum.

Preserves activity in the presence of purulent sputum.

It has an antioxidant effect due to the presence of the SH group capable of neutralizing electrophilic oxidative toxins.

It also has an anti-inflammatory effect (due to the suppression of the formation of free radicals and active oxygen-containing substances responsible for the development of inflammation in the lung tissue).

Indications

Diseases of the respiratory system, accompanied by the formation of sputum of increased viscosity (acute and chronic bronchitis, pneumonia, bronchiectasis, cystic fibrosis, bronchial asthma) to facilitate mucus discharge in sinusitis.

Diseases of the respiratory system, accompanied by the formation of sputum with increased viscosity.

Contraindications

Hypersensitivity to acetylcysteine, peptic ulcer of the stomach and duodenum in the acute stage.

Caution should be given to patients with liver and kidney disease.

Use during pregnancy and lactation

Use during pregnancy and breastfeeding is only possible if the intended benefits to the mother outweigh the potential risk to the fetus or baby.

Special instructions

For patients with bronchial asthma and obstructive bronchitis, Fluimucil can only be prescribed if adequate sputum drainage is provided.

Dosage forms for oral administration contain aspartame, therefore, they should not be prescribed to patients with phenylketonuria.

When dissolving the drug, use glassware and avoid contact with metal and rubber surfaces. When opening the bag with granules, the smell of sulfur is possible, which is the smell of the active substance, and not evidence of poor quality of the drug.

Composition

One packet contains: active substance:

acetylcysteine ??- 200 mg

excipients:

aspartame 25 mg,

betacarotene 12.3 mg,

flavoring orange 62,

flavoring orange62 7 mg

Dosage and administration

Granules for oral solution are dissolved in 1/3 cup of water.

Adults and children over 6 years of age - 200 mg 2-3 times a day.

Newborns - only for health reasons at a dose of 10 mg / kg under strict medical supervision. Children of the first year of life are given the solution to drink from a spoon or bottle for feeding. Children from 1 year to 2 years - 100 mg 2 times a day, from 2 to 6 years - 200 mg 2 times a day or 100 mg 3 times a day.

Duration of treatment should be evaluated individually. In acute diseases, the duration of treatment is from 5 to 10 days and up to several months in the treatment of chronic diseases (on the recommendation of a doctor).

Side effects

From the digestive system: rarely - heartburn, nausea, vomiting, diarrhea, stomatitis.

Allergic reactions: rarely - skin rash, itching, urticaria, bronchospasm.

Other: rarely - nosebleeds, tinnitus, collapse, decreased platelet aggregation.

Local reactions: with parenteral administration, a slight burning sensation at the injection site is possible with inhalation administration - a reflex cough, local respiratory tract irritation, stomatitis, rarely rhinitis - bronchospasm (in this case, the appointment of bronchodilators is necessary).

Drug interactions

The combined use of acetylcysteine ​​with antitussive agents can increase sputum congestion due to suppression of the cough reflex.

When used simultaneously with antibiotics such as tetracyclines (excluding doxycycline), ampicillin, amphotericin B, their interaction with the thiol group of acetylcysteine ​​is possible, which leads to a decrease in the activity of both drugs. Therefore, the interval between doses of these drugs should be at least 2 hours.

The simultaneous use of acetylcysteine ​​and nitroglycerin can cause a pronounced decrease in blood pressure and headache.

Concomitant use of acetylcysteine ​​and carbamazepine may result in subtherapeutic levels of carbamazepine.

Activated carbon can reduce the effect of acetylcysteine.

Acetylcysteine ​​eliminates the toxic effects of paracetamol.

Acetylcysteine ​​may affect the colorimetric results of salicylates.

Acetylcysteine ​​may affect urine ketone analysis.

Overdose

Acetylcysteine, when taken at a dose of 500 mg / kg / day, does not cause signs and symptoms of overdose.

Symptoms

The following symptoms may occur: nausea, vomiting and diarrhea.

Treatment: There is no specific antidote, the treatment is symptomatic.

Storage conditions

In a dark place at a temperature not exceeding 25 РC.

Shelf life

3 years.

Terms and conditions otpuska IZ

pharmacies without a prescription

Possible product names

Fluimucil 200MG. No. 20 GRAN. D / R-RA

Fluimucil granules for solution for oral administration 200 mg sachet 20 pcs.

Zambon S.p.A., Italy

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