Freeze-dried vaccine against Marek's disease with Avivak Marek-3 diluent (1000 doses) 2 vials

DESCRIPTION

Vaccine against Marek's disease AVIVAC-Marek dry culture with a diluent. In appearance, the vaccine is a homogeneous fine-pored mass of white-yellow color.

COMPOSITION

The AVIVAC-Marek vaccine is made from a culture of quail embryo fibroblasts cells infected with turkey herpesvirus (VGI strain 'FS-126'), disintegrated by ultrasound and freeze-dried with the addition of a stabilizer, which contains sucrose and gelatose solutions in buffer.

The vaccine is supplied complete with a diluent (AVIVAC-Marek Diluent), which includes phosphate-buffered saline pH 7.0-7.4, sucrose, peptone, phenol red. In appearance, the diluent is a clear orange-red liquid.

BIOLOGICAL PROPERTIES

In vaccinated chickens, the vaccine induces the formation of immunity to Marek's disease on the 14th day, which lasts for life. The vaccine in the recommended dose is harmless and areactogenic; does not possess medicinal properties.

A vaccine with an infectious activity of at least 2.5x10 FRU / cm3 is suitable for use. One immunizing dose of the vaccine is 2000 FRU.

APPLICATION

The vaccine is used to immunize chickens in prosperous, threatened and dysfunctional farms of various cultivation areas due to Marek's disease.

Chickens are vaccinated in the first hours of life once, directly in the hatchery in a specially adapted room. The vaccine is administered intramuscularly using syringes or special automatic injectors in the upper third of the inner thigh or subcutaneously in the upper third of the neck in a volume of 0.2 cm3. In the presence of Ovodzhek-type injection equipment, it is recommended to inject the drug directly into the embryo on the 18th day of incubation.

Vaccination Vials with a diluent in the amount required for vaccination are kept for 8-12 hours at a temperature of 18-25 В° C before use. Before vaccination, 2.0 cm of diluent is added to the vaccine vial using a sterile syringe. After resuspension, the vaccine is combined with the bulk of the diluent. The contents of the vials with the vaccine are dissolved in one vial of the diluent at the rate of: in 200.0 cm3 - 1000 doses; 400.0 cm3 - 2000 doses. The diluted vaccine vials are protected from direct sunlight and heat. During vaccination, the diluted vaccine vials are periodically shaken without foaming. Before vaccination, syringes and needles are sterilized by boiling in distilled water for 10-15 minutes, and injectors that cannot be boiled are disassembled, cleaned, washed with cooled boiled water,

During the first 3 weeks, vaccinated chickens are kept in isolation from birds of other age groups.

PERSONAL PREVENTION MEASURES

All persons participating in the vaccination must wear special clothing (dressing gown, trousers, hat, rubber gloves). During vaccination, it is prohibited to eat, drink, smoke.

If the vaccine gets on the exposed skin of the hands and face, as well as their mucous membranes, it is recommended to rinse them with plenty of tap water. In case of a vaccine spill, the contaminated area of ​​the floor or soil is poured with a 5% solution of chloramine or sodium hydroxide.

In case of accidental administration of the drug to a person, he should contact a medical institution and inform a doctor about it.

SHELF LIFE AND STORAGE

The shelf life of the vaccine is 12 months from the date of manufacture, provided that it is stored and transported at a temperature of 2 to 6 В° C. Expiration date of the diluent is 24 months from the date of manufacture, provided that it is stored and transported in a dry, dark place at a temperature of 8 to 12 В° C. Do not use an expired vaccine or diluent.

PACKAGING

The vaccine is packaged in 5.0 ml glass vials of appropriate capacity (1000 doses each). The vials are sealed with rubber stoppers, reinforced with aluminum caps.

The thinner is packaged in 200 ml bottles. The vials are sealed with rubber stoppers, reinforced with aluminum caps.

Specifications

Bonus points

0

KolVUP

1

Manufacturer

AVIVAC

Temperature regime

from +2 to +8

Teaser

for immunization of chickens against Marek's disease